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Ketopremithramycins and ketomithramycins; four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces Argillaceus; reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway
| dc.contributor.author | Remsing, Lily | |
| dc.contributor.author | García-Bernardo Junquera, José | |
| dc.contributor.author | González, A. | |
| dc.contributor.author | Künzel, Eva | |
| dc.contributor.author | Rix, Uwe | |
| dc.contributor.author | Fernández Braña, Alfredo Javier | |
| dc.contributor.author | Bearden, D. W. | |
| dc.contributor.author | Méndez Fernández, María del Carmen | |
| dc.contributor.author | Salas Fernández, José Antonio | |
| dc.contributor.author | Rohr, Jürgen | |
| dc.date.accessioned | 2017-04-24T11:44:59Z | |
| dc.date.available | 2017-04-24T11:44:59Z | |
| dc.date.issued | 2002 | |
| dc.identifier.citation | Journal of the American Chemical Society, 124(8), p. 1606-1614 (2002); doi:10.1021/ja0105156 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/10651/42083 | |
| dc.description.sponsorship | This work was supported by grants of the South Carolina Commission of Higher Education (2000−2001), the U.S. Department of Defense, and the National Institutes of Health (R01CA91901) to J.R., and by the Spanish Ministry of Education and Science to J.A.S. through the “Plan Nacional en Biotecnologia” (R01CA91901). Drs. William Cotham and Michael Walla, Department of Chemistry and Biochemistry, University of South Carolina, are acknowledged for recording the FAB mass spectra. | |
| dc.format.extent | p. 1606-1614 | |
| dc.language.iso | eng | |
| dc.publisher | American Chemical Society | |
| dc.relation.ispartof | Journal of the American Chemical Society | |
| dc.rights | © | |
| dc.source | Scopus | |
| dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037181040&doi=10.1021%2fja0105156&partnerID=40&md5=2a20ebd7b42d5957b1840f10df877297 | |
| dc.title | Ketopremithramycins and ketomithramycins; four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces Argillaceus; reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway | |
| dc.type | journal article | |
| dc.identifier.doi | 10.1021/ja0105156 | |
| dc.relation.projectID | R01CA91901 | |
| dc.relation.projectID | BIO97-0771 | |
| dc.relation.publisherversion | http://dx.doi.org/10.1021/ja0105156 |
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