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Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome

dc.contributor.authorSantiago Fernández, Olaya 
dc.contributor.authorGarcía Osorio, Fernando 
dc.contributor.authorQuesada Fernández, Víctor 
dc.contributor.authorRodríguez, Francisco
dc.contributor.authorBasso, Sammy
dc.contributor.authorMaeso Miguel, Daniel 
dc.contributor.authorRolas, Loïc
dc.contributor.authorBarkaway, Anna
dc.contributor.authorNourshargh, Sussan
dc.contributor.authorRodríguez Folgueras, Alicia 
dc.contributor.authorPérez Freije, José María 
dc.contributor.authorLópez Otín, Carlos 
dc.date.accessioned2019-06-14T07:02:51Z
dc.date.available2019-06-14T07:02:51Z
dc.date.issued2019
dc.identifier.citationNature medicine, 25, p. 423–426 (2019); doi:10.1038/s41591-018-0338-6
dc.identifier.issn1078-8956
dc.identifier.urihttp://hdl.handle.net/10651/51392
dc.description.sponsorshipThe Instituto Universitario de Oncología del Principado de Asturias is supported by Fundación Bancaria Caja de Ahorros de Asturias. J.M.P.F. is supported by Ministerio de Economía y Competitividad (MINECO/FEDER: No. SAF2015-64157-R) and Gobierno del Principado de Asturias. C.L.-O. is supported by grants from the European Research Council (ERC-2016-ADG, DeAge), Ministerio de Economía y Competitividad (MINECO/FEDER: Nos. SAF2014-52413-R and SAF2017-87655-R), Instituto de Salud Carlos III (RTICC) and Progeria Research Foundation (No. PRF2016-66). O.S.-F. is recipient of an FPU fellowship. A.R.F. is recipient of a Ramón y Cajal fellowship. The generation of progerin antibody was funded by the Wellcome Trust (No. 098291/Z/12/Z to S.N.).spa
dc.format.extentp. 423–426spa
dc.language.isoengspa
dc.relation.ispartofNature medicine, 25spa
dc.rights© 2019, Springer Nature
dc.titleDevelopment of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndromespa
dc.typejournal articlespa
dc.identifier.doi10.1038/s41591-018-0338-6
dc.relation.projectIDERC-2016-ADGspa
dc.relation.projectIDMINECO/FEDER/SAF2014-52413-R
dc.relation.projectIDMINECO/FEDER/SAF2017-87655-R
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/742067
dc.relation.publisherversionhttps://doi.org/10.1038/s41591-018-0338-6spa
dc.rights.accessRightsopen access
dc.type.hasVersionAM


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