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Integrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia

dc.contributor.authorTejedor Vaquero, Juan Ramón 
dc.contributor.authorBueno, Clara
dc.contributor.authorVinyoles, M.
dc.contributor.authorPetazzi, P.
dc.contributor.authorAgraz Doblas, A.
dc.contributor.authorCobo, I.
dc.contributor.authorTorres Ruiz, R.
dc.contributor.authorFernández Bayón, Gustavo 
dc.contributor.authorFernández Pérez, Raúl
dc.contributor.authorLópez Tamargo, Sara 
dc.contributor.authorGutiérrez Agüera, F.
dc.contributor.authorSantamarina Ojeda, P.
dc.contributor.authorRamírez Orellana, M.
dc.contributor.authorBardini, M.
dc.contributor.authorCazzaniga, G.
dc.contributor.authorBallerini, P.
dc.contributor.authorSchneider, P.
dc.contributor.authorStam, R. W.
dc.contributor.authorVarela, I.
dc.contributor.authorFernández Fraga, Mario 
dc.contributor.authorFernández Fernández, Agustín 
dc.contributor.authorMenéndez, P.
dc.date.accessioned2022-02-01T08:05:22Z
dc.date.available2022-02-01T08:05:22Z
dc.date.issued2021
dc.identifier.citationJournal of Clinical Investigation, 131(13) (2021); doi:10.1172/JCI138833
dc.identifier.issn0021-9738
dc.identifier.urihttp://hdl.handle.net/10651/61633
dc.description.sponsorshipFinancial support for this work was obtained from the European Research Council (CoG-2014-646903 and PoC-2018-811220 to PM), the Spanish Ministry of Economy and Competitiveness (SAF2019-108160-R and SAF2016-76758-R to PM and IV, respectively), the Spanish Association against cancer (AECC-CI-2015 and PROYE18061FERN to CB and MFF), the Fundación Uno entre Cienmil (to PM), the Health Institute Carlos III (ISCIII/FEDER, PI17/01028, PI15/00892, PI18/01527 to CB and AFF/MFF, respectively). We also acknowledge the Plan de Ciencia, Tecnología e Innovación from the Asturias Government cofunding 2018–2022/FEDER (IDI/2018/146 to MFF). JRT and MV are supported by Juan de la Cierva fellowships by the Spanish Ministry of Science and Innovation (FJCI-2015-26965, IJC2018-36825-I, IJCI-2017-3317) and IUOPA-ISPA-FINBA. RTR is supported by a fellowship from the AECC scientific foundation. RFP and PSO are supported by the Severo Ochoa program (BP17-114 and BP17-165, respectively)...
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Investigation
dc.rights© 2021 American Society for Clinical Investigation
dc.sourceScopus
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85109003849&doi=10.1172%2fJCI138833&partnerID=40&md5=4b3a7fb0c1c8997bf9cee0a117147c9f
dc.titleIntegrative methylome-transcriptome analysis unravels cancer cell vulnerabilities in infant MLL-rearranged B cell acute lymphoblastic leukemia
dc.typejournal article
dc.identifier.doi10.1172/JCI138833
dc.relation.projectIDERC/CoG-2014-646903
dc.relation.projectIDERC/PoC-2018-811220
dc.relation.projectIDMINECO/SAF2019-108160-R
dc.relation.projectIDMINECO/SAF2016-76758-R
dc.relation.projectIDISCIII/FEDER/PI17/01028
dc.relation.projectIDISCIII/FEDER/PI15/00892
dc.relation.projectIDISCIII/FEDER/PI18/01527
dc.relation.publisherversionhttp://dx.doi.org/10.1172/JCI138833


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