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Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β‑Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family

dc.contributor.authorBecerril García, Adriana 
dc.contributor.authorPérez Victoria, I.
dc.contributor.authorMartín, J. M.
dc.contributor.authorReyes, F.
dc.contributor.authorSalas Fernández, José Antonio 
dc.contributor.authorMéndez Fernández, María del Carmen 
dc.date.accessioned2023-03-02T09:29:46Z
dc.date.available2023-03-02T09:29:46Z
dc.date.issued2022
dc.identifier.citationACS Chemical Biology, 17(8), p. 2320-2331 (2022); doi:10.1021/acschembio.2c00416
dc.identifier.issn1554-8929
dc.identifier.urihttp://hdl.handle.net/10651/66659
dc.description.sponsorshiphis work was supported by grants from the Spanish Ministry of Economy and Competitiveness, MINECO (Grants BIO2014-56752-R, BIO2017-82462-R, and PID2020- 113062RB-100 to C.M.), by the grant “Apoyo a grupos de excelencia”, Principado de Asturias-FEDER (FC-15-GRU- PIN14-014), and by the grant PAPI-20-GR-2010-0019 from Universidad de Oviedo. A.B. was recipient of a predoctoral fellowship from MINECO (FPU13/00831).
dc.format.extentp. 2320-2331
dc.language.isoeng
dc.relation.ispartofACS Chemical Biology
dc.rights© 2022 The Authors. Published by American Chemical Society
dc.rightsCC Reconocimiento 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScopus
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85135207890&doi=10.1021%2facschembio.2c00416&partnerID=40&md5=4908ad4520e186398a2580185e1c22ae
dc.titleBiosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β‑Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family
dc.typejournal article
dc.identifier.doi10.1021/acschembio.2c00416
dc.local.notesOA ATUO22
dc.relation.projectIDMINECO/BIO2014-56752-R
dc.relation.projectIDMINECO/BIO2017-82462-R
dc.relation.projectIDMINECO/PID2020-113062RB-100
dc.relation.projectIDFICYT/FEDER/FC-15-GRUPIN14-014
dc.relation.projectIDMINECO/FPU13/00831
dc.relation.publisherversionhttp://dx.doi.org/10.1021/acschembio.2c00416
dc.rights.accessRightsopen access
dc.type.hasVersionVoR


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© 2022 The Authors. Published by American Chemical Society
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